Terreic acid biosynthesis
Web29 Sep 2014 · Terreic acid is a natural product derived from 6-methylsalicylic acid (6-MSA). A compact gene cluster for its biosynthesis was characterized. Isolation of the … WebBiological Activity for (-)-Terreic acid. (-)-Terreic acid is a selective inhibitor of Bruton's tyrosine kinase (BTK). Inhibits the interaction between PKCbII and BTK (IC 50 ~ 30 mM) …
Terreic acid biosynthesis
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Web6-methylsalicylic acid synthase; part of the gene cluster that mediates the biosynthesis of terreic acid, a quinone epoxide inhibitor of Bruton's tyrosine kinase (PubMed:24534845, … Web26 Jul 2016 · The biosynthesis pathways of nine PKS genes have been reported, and their downstream metabolites are lovastatin, terreic acid, terrein, geodin, terretonin, …
Web27 Jan 2015 · For nucleic acid biosynthesis, which is energetically costly, the nucleotide synthesis consumes 0.5–9 pmol exogenous carbon, which is comparable in number to the ATP hydrolysis. Thus, to make nucleic acids for cell proliferation purposes, cells have to upregulate both energy metabolism and the nucleotide biosynthetic pathways. ... WebABSTRACT: Terreic acid is a natural product derived from 6methylsalicylic acid (6-MSA). A compact gene cluster for its biosynthesis was characterized. Isolation of the intermediates and shunt products from the mutant strains, combined with bioinformatic analyses, allowed for the proposition of a biosynthetic pathway for terreic acid.
WebThe individual reactions of terreic acid biosynthesis were determined by stepwise pathway assembly in a heterologous host on the basis of previous knockout studies in a native … Webcore biosynthetic genes additional biosynthetic genes transport-related genes regulatory genes other genes resistance reset view zoom to selection Gene details Select a gene to view the details available for it General Compounds Genes Polyketide History NRPS/PKS domains KnownClusterBlast Modifications General information about the BGC
Web8 Mar 2024 · Succinic acid, a dicarboxylic acid produced as an intermediate of the tricarboxylic acid (TCA) cycle, is one of the most important platform chemicals for the …
WebAmong them, lovastatin is a well-known hypolipidemic agent. Terreic acid, terrein, citreoviridin, and asperfuranone show good bioactivities, especially anticancer activities. … men\u0027s snowshoe size chartWebPubMed men\u0027s soap on a ropeWebTerreic acid (TA) is a covalent inhibitor of the bacterial cell wall biosynthetic enzyme MurA. The survival of most bacteria depends on the functionality of this cytosolic enzyme. The … men\u0027s soccer division 3 rankingsWebHeterologous pathway assembly reveals molecular steps of fungal terreic acid biosynthesis. Kong C et al., Sci Rep (2024) PMID:29391515 Cloning of the polyketide synthase gene atX … how much water does a betta needWebeach comonomer comprises a hydrocarbylene group wherein one or more methylene groups of the hydrocarbylene group is optionally replaced by a group Y (provided that none of the Y g how much water does a beef cow drink a dayWebTerreic acid by Bioviotica, Product code: BVT-0477 distributed by Caltag Medsystems Limited. how much water does a bathtub useWebTerreic acid, terrein, citreoviridin, and asperfuranone show good bioactivities, especially anticancer activities. On the other hand, geodin and terretonin are mycotoxins. So, … how much water does a bath use vs a shower