Tamm-horsfall protein deposition
WebOct 1, 2003 · 1987. TLDR. Uromodulin (Tamm-Horsfall glycoprotein) may function as a unique renal regulatory glycop protein that specifically binds to and regulates the circulating activity of a number of potent cytokines, including IL-1 and TNF. 262. WebTamm-Horsfall Urinary Mucoprotein—Role in Renal Tubular Blockage by Casts. While seeking viral inhibitory agents, Tamm and Horsfall (16) discovered in 1950 a urinary mucoprotein that was readily precipitated by relatively low sodium concentration. T.H. protein, subsequently found in every mammalian species, is a polymeric structure, rod-like …
Tamm-horsfall protein deposition
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WebMar 17, 2014 · Calcium oxalate crystals deposition was observed in both renal cortex and medulla. Immunohistochemistry examination revealed increased tissue expression of OPN in the renal tissue while THP was significantly decreased. ... Osteopontin (OPN) and Tamm-Horsfall protein (THP) are the most important proteins involved in this process. Although … WebFeb 21, 2024 · Nephrotic-range proteinuria Urine total protein: ≥3.5 g/day. The presence of nephrotic-range proteinuria with edema, hypoalbuminemia (<3.0 g/dL), and hyperlipidemia is defined as nephrotic syndrome. …
WebAbstract Tamm-Horsfall protein (THP) is exclusively produced by renal tubular cells of the distal loop of Henle and is the most abundant urinary protein in mammals. WebMar 17, 2014 · Abnormal localization and increased expression of Tamm–Horsfall Protein, osteopontin and transferrin were observed in the kidneys of urolithic rats (P < .001) from immunohistochemistry and ...
WebTamm-Horsfall protein (THP) is a high-molecular-weight glycoprotein synthesized exclusively by the ascending loop of Henle and the distal tubule of normal kidney. In pathologic conditions, THP may accumulate in renal parenchyma, perirenal soft tissue, or renal hilar lymph nodes. WebSep 26, 2012 · Tamm-Horsfall Protein (THP) is urine's most abundant protein and is known to bind to uropathogenic bacteria. The role of THP in the pathogenesis of catheter …
WebApr 11, 2024 · After the colonization of uropathogens, the preliminary step of UTI relies on adhesins, especially type I fimbriae, which enable uropathogens to recognize specific extracellular matrix proteins (laminin, fibronectin, collagen, and Tamm–Horsfall proteins) on the bladder epithelium, thereby binding to uroepithelial cells [ 27, 28 ].
WebOct 3, 2003 · Tamm-Horsfall protein (THP) is a glycoprotein present abundantly in human urine. It is localized in the thick ascending limb of the loop of Henle (TAL) and the early distal convoluted tubule (DCT). The rate of urinary excretion of THP has been studied in various diabetic groups. オブジェクト指向 継承Web摘要：. 目的:探讨乌梅提取物对纳米细菌致肾结石大鼠Tamm-Horsfall (THP)蛋白表达的影响。. 方法:将45只SD雄性大鼠随机分为空白组、对照组和实验组各15只。. 对照组和实验组尾静脉注射纳米细菌混悬液1 mL制备大鼠肾结石模型，对照组大鼠尾静脉注射等量生理盐水 ... parenzo giulietto chiesaWebUromodulin is recognized as a protective factor during AKI-to-CKD progression, but the mechanism remains unclear. We previously reported that uromodulin interacts with complement factor H (CFH) in vitro, and currently aimed to study the expression and interaction evolution of uromodulin and CFH during AKI-to-CKD transition. We … オブジェクト指向 終わりWebSep 26, 2012 · Tamm-Horsfall Protein (THP) is urine's most abundant protein and is known to bind to uropathogenic bacteria. The role of THP in the pathogenesis of catheter associated urinary tract infection (CAUTI) is not clear. We examined the role of THP in facilitating bacterial binding to urinary catheters in vivo and in vitro. Findings オブジェクト指向言語 なぜparenzo immaginiWebJan 22, 2024 · Tamm–Horsfall protein (THP), or uromodulin (UMOD), is an 80–90-kDa phosphatidylinositol-anchored glycoprotein produced exclusively by the renal tubular cells in the thick ascending limb of the ... parenzo instagramWebMay 1, 1985 · A case in which unusually large deposits of Tamm-Horsfall protein were identified in perinephric adipose tissue is presented. The deposition around the kidney in … parenzo invest