WebGalactonate. d-Galactonate dehydratase (GalD) from E. coli catalyzes anti-dehydration involving base-catalyzed proton abstraction from C-2 and acid-catalyzed departure of the … WebJan 28, 2024 · d-Galactonate, an aldonic sugar acid, is used as a carbon source by Escherichia coli, and the structural dgo genes involved in its metabolism have previously been investigated. Here, using genetic, biochemical and bioinformatics approaches, we present the first detailed molecular and functional insights into the regulation of d …
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WebNov 7, 2008 · The purified recombinant aldonolactonase expressed in Escherichia coli catalyzed the reversible reaction of L-galactonate and L-galactono-1,4-lactone with zinc … WebOct 17, 2024 · D-galactonate binds DgoR and induces a conformational change in the protein to release the dgo operator (Singh et al., 2024). FIGURE 1. Open in figure viewer PowerPoint. Random mutagenesis screen identifies DgoR mutants that behave as superrepressors. (a) Model depicting the regulation of D-galactonate metabolism by DgoR. haarjeet
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WebThe red blood cell (RBC) concentration of galactitol and galactonate was measured in 27 patients with galactose-1-phosphate uridyltransferase (GALT) deficiency galactosemia … Web2-Dehydro-3-deoxy-D-galactonate 6-phosphate is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). 6-phosphonato-2-dehydro-3-deoxy-D-galactate (3-) is an organophosphate oxoanion that is a trianion obtained via deprotonation of the carboxy and phosphate OH groups of 6-phospho-2-dehydro-3-deoxy-D-galactonic acid; major ... WebAug 26, 2010 · Keto-deoxy-L-galactonate is an intermediate in the metabolism of D-galacturonate by fungi and the genes encoding D-galacturonate reductase (gar1 & gaaA), L-galactonate dehydratase (lgd1 & gaaB) and 2-keto-3-deoxy-L-galactonate aldolase (lga1 & gaaC) have been identified in Trichoderma reesei (anamorph of Hypocrea jecorina) [3, 9, … haarkämme aus horn